InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc26a11

Summary

InnateDB Protein

IDBP-214704.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc26a11

Protein Name

solute carrier family 26, member 11

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000050999

InnateDB Gene

IDBG-214702 (Slc26a11)

Protein Structure

UniProt Annotation

Function

Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). {ECO:0000250UniProtKB:Q86WA9}.

Subcellular Localization

Cell membrane {ECO:0000250UniProtKB:Q86WA9}; Multi-pass membrane protein {ECO:0000250UniProtKB:Q86WA9}. Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250UniProtKB:Q86WA9}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008271	secondary active sulfate transmembrane transporter activity
GO:0008509	anion transmembrane transporter activity
GO:0015116	sulfate transmembrane transporter activity
GO:0015301	anion:anion antiporter activity

Biological Process

GO:0008272	sulfate transport
GO:1902358	sulfate transmembrane transport

Cellular Component

GO:0005765	lysosomal membrane
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome