Version 5.4
Mus musculus Protein: Nptx1
Summary
InnateDB Protein IDBP-214723.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nptx1
Protein Name neuronal pentraxin 1
Synonyms D11Bwg1004e; Np1;
Species Mus musculus
Ensembl Protein ENSMUSP00000026670
InnateDB Gene IDBG-214721 (Nptx1)
Protein Structure
UniProt Annotation
Function May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, secretory vesicle {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006839 mitochondrial transport
GO:0035865 cellular response to potassium ion
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0060385 axonogenesis involved in innervation
GO:0071333 cellular response to glucose stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0030133 transport vesicle
GO:0043005 neuron projection
Protein Structure and Domains
PDB ID MGI:107811
InterPro IPR001759 Pentaxin
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00354
PRINTS PR00895
PIRSF
SMART SM00159
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q62443
PhosphoSite PhosphoSite-Q62443
TrEMBL Q3UST4
UniProt Splice Variant
Entrez Gene 18164
UniGene Mm.5142
RefSeq NP_032756
MGI ID
MGI Symbol Nptx1
OMIM
CCDS CCDS25719
HPRD
IMGT
EMBL AK140128 BC093479 BC139018 BC139020 CH466558 U62021
GenPept AAC52826 AAH93479 AAI39019 AAI39021 BAE24247 EDL34711

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca