Version 5.4
Mus musculus Protein: Zfp750
Summary
InnateDB Protein IDBP-214999.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp750
Protein Name zinc finger protein 750
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000089951
InnateDB Gene IDBG-214997 (Zfp750)
Protein Structure
UniProt Annotation
Function Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0008544 epidermis development
GO:0030154 cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2442210
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BH05
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 319530
UniGene Mm.446474
RefSeq NP_848878
MGI ID
MGI Symbol Zfp750
OMIM
CCDS CCDS25779
HPRD
IMGT
EMBL AK030690 AK037185 AK037240 AL663088 BC150905
GenPept AAI50906 BAC27080 BAC29743 BAC29771 CAM19958

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca