InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: mt-Nd1

Summary

InnateDB Protein

IDBP-215017.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

mt-Nd1

Protein Name

mitochondrially encoded NADH dehydrogenase 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000080991

InnateDB Gene

IDBG-215015 (mt-Nd1)

Protein Structure

UniProt Annotation

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008137	NADH dehydrogenase (ubiquinone) activity

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005747	mitochondrial respiratory chain complex I
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane