Version 5.4
Mus musculus Protein: mt-Nd3
Summary
InnateDB Protein IDBP-215038.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol mt-Nd3
Protein Name mitochondrially encoded NADH dehydrogenase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000080998
InnateDB Gene IDBG-215036 (mt-Nd3)
Protein Structure
UniProt Annotation
Function Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005747 mitochondrial respiratory chain complex I
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:102499
InterPro IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3
PFAM PF00507
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P03899
PhosphoSite PhosphoSite-
TrEMBL Q7GIP5
UniProt Splice Variant
Entrez Gene 17718
UniGene Mm.489752
RefSeq NP_904335
MGI ID
MGI Symbol mt-Nd3
OMIM
CCDS
HPRD
IMGT
EMBL AB042432 AB042523 AB042524 AB042809 AB049357 AJ489607 AJ512208 AK139029 AP013030 AP013031 AP013054 AP014540 AP014541 AY172335 AY339599 AY466499 AY533105 AY533106 AY533107 AY533108 AY836751 AY836752 AY999076 DQ106412 DQ106413 EF108330 EF108331 EF108332 EF108333 EF108334 EF108335 EF108336 EF108337 EF108338 EF108339 EF108340 EF108341 EU312160 EU312161 EU315228 EU315229 EU450583 FJ803909 HQ586004 HQ675026 HQ675027 HQ675028 HQ675029 HQ675030 HQ675031 HQ877407 J01420 JF286601 JQ003190 KC415992 U09637 U09638 V00711
GenPept AAA19254 AAA19255 AAB48651 AAN85129 AAP89030 AAR21202 AAS01433 AAS01446 AAS01459 AAS01472 AAW21323 AAW21326 AAX83019 AAY96696 AAY96709 ABK79100 ABK79113 ABK79126 ABK79139 ABK79152 ABK79165 ABK79178 ABK79191 ABK79204 ABK79217 ABK79230 ABK79243 ABX79709 ABX79722 ABX79735 ABX79748 ACA01530 ACN91102 ADR03163 ADW83073 ADZ23171 AEN03376 AEN03389 AEN03402 AEN03415 AEN03428 AEN03441 AEV56604 AGI15881 BAA95623 BAA95647 BAA95660 BAA95802 BAB13808 BAE23869 BAM93590 BAM93603 BAN16599 BAO42857 BAO42870 CAA24086 CAD33914 CAD54439

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca