Version 5.4
Homo sapiens Protein: IL6ST
Summary
InnateDB Protein IDBP-21524.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL6ST
Protein Name interleukin 6 signal transducer (gp130, oncostatin M receptor)
Synonyms CD130; CDW130; GP130; IL-6RB;
Species Homo sapiens
Ensembl Protein ENSP00000370693
InnateDB Gene IDBG-21516 (IL6ST)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 56 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 56 [view]
Protein-Protein 53 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR010457 Immunoglobulin C2-set-like, ligand-binding
PFAM PF00041
PF01108
PF06328
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q5FC05
TrEMBL Q5FC05
UniProt Splice Variant
Entrez Gene 3572
UniGene Hs.708507
RefSeq
HUGO HGNC:6021
OMIM 600694
CCDS
HPRD 02824
IMGT
EMBL AB102801 AC008914 AC016596
GenPept BAD89392

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca