Version 5.4
Homo sapiens Protein: KLHL14
Summary
InnateDB Protein IDBP-2266.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL14
Protein Name kelch-like 14 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000350808
InnateDB Gene IDBG-2258 (KLHL14)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, cytosol {ECO:0000269PubMed:19535332}. Endoplasmic reticulum membrane {ECO:0000269PubMed:19535332}. Note=Colocalizes with TOR1A at the endoplasmic reticulum level.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR011333 BTB/POZ fold
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
PFAM PF07707
PF00651
PRINTS
PIRSF
SMART SM00225
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P2G3
PhosphoSite PhosphoSite-Q9P2G3
TrEMBL
UniProt Splice Variant
Entrez Gene 57565
UniGene Hs.610568
RefSeq
HUGO HGNC:29266
OMIM 613772
CCDS
HPRD 17238
IMGT
EMBL AB037805 AC025887 AK294996 BC021267 CH471088
GenPept AAH21267 BAA92622 BAG58061 EAX01295 EAX01296

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca