Version 5.4
Homo sapiens Protein: SLC2A7
Summary
InnateDB Protein IDBP-227117.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC2A7
Protein Name solute carrier family 2 (facilitated glucose transporter), member 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000383698
InnateDB Gene IDBG-88453 (SLC2A7)
Protein Structure
UniProt Annotation
Function High-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose. {ECO:0000269PubMed:15033637}.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Expressed in small intestine and colon. Weakly expressed in testis and prostate. {ECO:0000269PubMed:15033637}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003663 Sugar/inositol transporter
IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF00083
PF07690
PRINTS PR00171
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PXP3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 155184
UniGene Hs.531239
RefSeq NP_997303
HUGO HGNC:13445
OMIM 610371
CCDS CCDS98
HPRD 15365
IMGT
EMBL AL158048 AY571960 CH471130
GenPept AAS78590 CAI23459 EAW71607

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca