InnateDB Protein
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IDBP-22877.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CCDC101
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Protein Name
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coiled-coil domain containing 101
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000316114
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InnateDB Gene
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IDBG-22875 (CCDC101)
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Protein Structure
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Function |
Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA- type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation. {ECO:0000269PubMed:19103755}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
23
[view]
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Protein-Protein |
23
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR010750
SGF29 tudor-like domain
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PFAM |
PF07039
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96ES7
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PhosphoSite |
PhosphoSite-Q96ES7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
112869
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UniGene |
Hs.655476
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RefSeq |
NP_612423
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HUGO |
HGNC:25156
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OMIM |
613374
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CCDS |
CCDS10635
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HPRD |
13996
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IMGT |
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EMBL |
AK057008
BC011981
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GenPept |
AAH11981
BAB71340
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