Version 5.4
Homo sapiens Protein: GOLT1B
Summary
InnateDB Protein IDBP-22880.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOLT1B
Protein Name golgi transport 1B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000229314
InnateDB Gene IDBG-22878 (GOLT1B)
Protein Structure
UniProt Annotation
Function May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:10406798}; Multi-pass membrane protein {ECO:0000269PubMed:10406798}.
Disease Associations
Tissue Specificity Widely expressed. Tends to be up-regulated in seminomas compared to normal testis. {ECO:0000269PubMed:12414650}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0007165 signal transduction
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007305 Vesicle transport protein, Got1/SFT2-like
PFAM PF04178
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y3E0
PhosphoSite PhosphoSite-Q9Y3E0
TrEMBL G3V1U5
UniProt Splice Variant
Entrez Gene 51026
UniGene Hs.631171
RefSeq NP_057156
HUGO HGNC:20175
OMIM 615078
CCDS CCDS8689
HPRD 13035
IMGT
EMBL AB097020 AC006559 AF068292 AF151899 AK311920 AL136571 AY358975 BC012455 CH471094 CR457389
GenPept AAD34136 AAF65181 AAH12455 AAQ89334 BAC77373 BAG34861 CAB66506 CAG33670 EAW96441 EAW96443

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca