Version 5.4
Homo sapiens Protein: ARGLU1
Summary
InnateDB Protein IDBP-228813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARGLU1
Protein Name arginine and glutamate rich 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000383059
InnateDB Gene IDBG-49638 (ARGLU1)
Protein Structure
UniProt Annotation
Function Required for the estrogen-dependent expression of ESR1 target genes. Can act in cooperation with MED1. {ECO:0000269PubMed:21454576}.
Subcellular Localization Nucleus {ECO:0000269PubMed:21454576}. Note=Recruited, in an estrogen-dependent manner, to ESR1 target gene promoters. Colocalizes with MED1.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NWB6
PhosphoSite PhosphoSite-Q9NWB6
TrEMBL A0A024RDW4
UniProt Splice Variant
Entrez Gene 55082
UniGene Hs.605829
RefSeq NP_060481
HUGO HGNC:25482
OMIM 614046
CCDS CCDS41906
HPRD 07648
IMGT
EMBL AK001016 AK303575 AL442127 BC050434 BC071587 CH471085
GenPept AAH50434 AAH71587 BAA91467 BAG64595 CAI13166 CAI13168 EAX09086 EAX09087

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca