InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: L3MBTL4

Summary

InnateDB Protein

IDBP-229032.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

L3MBTL4

Protein Name

l(3)mbt-like 4 (Drosophila)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000382976

InnateDB Gene

IDBG-551 (L3MBTL4)

Protein Structure

UniProt Annotation

Function

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0016568	chromatin modification

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001660 Sterile alpha motif domain
IPR002515 Zinc finger, C2HC-type
IPR004092 Mbt repeat
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1

PFAM

PF01530
PF02820
PF07647
PF00536

PRINTS

PIRSF

SMART

SM00454
SM00561

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8NA19