Version 5.4
Homo sapiens Protein: TMEM57
Summary
InnateDB Protein IDBP-229827.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM57
Protein Name transmembrane protein 57
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000382668
InnateDB Gene IDBG-94344 (TMEM57)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, axon {ECO:0000250}. Note=Detected in the nucleus membrane of non- neuronal cells and in axonal outgrowths of neuronal cells. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0031965 nuclear membrane
GO:0044306 neuron projection terminus
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR009053 Prefoldin
IPR019130 Macoilin
PFAM PF09726
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N5G2
PhosphoSite PhosphoSite-Q8N5G2
TrEMBL Q9H5V1
UniProt Splice Variant
Entrez Gene 55219
UniGene Hs.189782
RefSeq NP_001269493
HUGO HGNC:25572
OMIM 610301
CCDS CCDS60034
HPRD 13340
IMGT
EMBL AK001609 AK026660 AL031284 AY845015 AY845035 AY845036 BC032427 BX572623 CH471059
GenPept AAH32427 AAX11913 AAX11933 AAX11934 BAA91786 BAB15518 CAM12861 CAM12862 EAX07876

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca