Homo sapiens Protein: SLC16A13
Summary
InnateDB Protein IDBP-23051.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC16A13
Protein Name solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000309751
InnateDB Gene IDBG-23049 (SLC16A13)
Protein Structure
UniProt Annotation
Function Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:24390345}; Multi-pass membrane protein {ECO:0000269PubMed:24390345}.
Disease Associations Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853]: A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. {ECO:0000269PubMed:24390345}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
IPR024671 Autophagy-related protein 22-like
PFAM PF07690
PF11700
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7RTY0
PhosphoSite PhosphoSite-Q7RTY0
TrEMBL
UniProt Splice Variant
Entrez Gene 201232
UniGene Hs.448010
RefSeq NP_963860
HUGO HGNC:31037
OMIM
CCDS CCDS11085
HPRD 18054
IMGT
EMBL BC109286 BC131739 BC142618 BN000145 CH471108
GenPept AAI09287 AAI31740 AAI42619 CAD80156 EAW90272