InnateDB Protein
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IDBP-231011.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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JMJD1C
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Protein Name
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jumonji domain containing 1C
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000382204
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InnateDB Gene
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IDBG-75649 (JMJD1C)
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Protein Structure
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Function |
Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
21
[view]
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Protein-Protein |
21
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003347
JmjC domain
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PFAM |
PF02373
PF08007
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PRINTS |
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PIRSF |
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SMART |
SM00558
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TIGRFAMs |
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Modification |
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SwissProt |
Q15652
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PhosphoSite |
PhosphoSite-Q15652
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
221037
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UniGene |
Hs.592714
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RefSeq |
NP_116165
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HUGO |
HGNC:12313
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OMIM |
604503
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CCDS |
CCDS41532
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HPRD |
05141
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IMGT |
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EMBL |
AB037801
AC022022
AK027280
AL590502
AL607128
AL713895
AL831917
BX537954
EF068222
L40411
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GenPept |
AAC41741
ABK64187
BAA92618
CAD38578
CAD97921
CAI10947
CAI10948
CAI10950
CAI14188
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