Version 5.4
Homo sapiens Protein: ZSWIM7
Summary
InnateDB Protein IDBP-231028.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZSWIM7
Protein Name zinc finger, SWIM-type containing 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000382218
InnateDB Gene IDBG-231024 (ZSWIM7)
Protein Structure
UniProt Annotation
Function Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. {ECO:0000269PubMed:16710300, ECO:0000269PubMed:21965664}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0050821 protein stabilization
Cellular Component
GO:0005634 nucleus
GO:0097196 Shu complex
Protein Structure and Domains
PDB ID
InterPro IPR007527 Zinc finger, SWIM-type
PFAM PF04434
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q19AV6
PhosphoSite PhosphoSite-Q19AV6
TrEMBL A0A024RD64
UniProt Splice Variant
Entrez Gene 125150
UniGene Hs.593985
RefSeq NP_001036163
HUGO HGNC:26993
OMIM 614535
CCDS CCDS42266
HPRD
IMGT
EMBL CH471222 DQ530600
GenPept ABF72190 EAX04486 EAX04487 EAX04488

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca