Version 5.4
Homo sapiens Protein: PPP1R18
Summary
InnateDB Protein IDBP-231202.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R18
Protein Name protein phosphatase 1, regulatory subunit 18
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000382150
InnateDB Gene IDBG-76628 (PPP1R18)
Protein Structure
UniProt Annotation
Function May target protein phosphatase 1 to F-actin cytoskeleton. {ECO:0000269PubMed:17374523}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000269PubMed:17374523}.
Disease Associations
Tissue Specificity Predominantly expressed in leukocytes and spleen. {ECO:0000269PubMed:17374523}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0019902 phosphatase binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NYC8
PhosphoSite PhosphoSite-Q6NYC8
TrEMBL A0A024RCJ8
UniProt Splice Variant
Entrez Gene 170954
UniGene Hs.101150
RefSeq NP_001128342
HUGO HGNC:29413
OMIM 610990
CCDS CCDS43444
HPRD
IMGT
EMBL AB073600 AB075829 AK124880 AK125639 AL662797 AL662798 AL732442 AL832318 AL845353 BC006176 BC066644 BX647622 BX908728 CH471081 CR753328 CR759873 CR788240 CR936878 DQ988947
GenPept AAH06176 AAH66644 ABL61261 BAB85535 BAC86229 BAD38640 BAG54110 CAD38613 CAI46080 CAM25008 CAM25509 CAM25551 CAQ06808 CAQ07426 CAQ07566 CAQ07800 CAQ08685 CAX11917 EAX03318 EAX03319

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca