InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HLA-DQB1

Summary

InnateDB Protein

IDBP-231501.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HLA-DQB1

Protein Name

major histocompatibility complex, class II, DQ beta 1

Synonyms

CELIAC1; HLA-DQB; IDDM1;

Species

Homo sapiens

Ensembl Protein

ENSP00000382029

InnateDB Gene

IDBG-81203 (HLA-DQB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955	immune response
GO:0019882	antigen processing and presentation

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042613	MHC class II protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000353 MHC class II, beta chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein

PFAM

PF00969
PF07654

PRINTS

PIRSF

SMART

SM00921
SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite