InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GXYLT1

Summary

InnateDB Protein

IDBP-232501.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GXYLT1

Protein Name

glucoside xylosyltransferase 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000381666

InnateDB Gene

IDBG-27651 (GXYLT1)

Protein Structure

UniProt Annotation

Function

Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. {ECO:0000269PubMed:19940119}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016757	transferase activity, transferring glycosyl groups
GO:0035252	UDP-xylosyltransferase activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0016266	O-glycan processing
GO:0030203	glycosaminoglycan metabolic process
GO:0030204	chondroitin sulfate metabolic process
GO:0044281	small molecule metabolic process