Version 5.4
| Homo sapiens Protein: FRMD4B | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-232829.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | FRMD4B | ||||||||
| Protein Name | FERM domain containing 4B | ||||||||
| Synonyms | 6030440G05Rik; GRSP1; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000381549 | ||||||||
| InnateDB Gene | IDBG-44041 (FRMD4B) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm, cytoskeleton {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000299
FERM domain IPR018979 FERM, N-terminal IPR018980 FERM, C-terminal PH-like domain IPR019748 FERM central domain IPR019749 Band 4.1 domain IPR019750 Band 4.1 family IPR021774 Protein of unknown function DUF3338 IPR029071 Ubiquitin-related domain |
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| PFAM |
PF09379
PF09380 PF00373 PF11819 |
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| PRINTS |
PR00935
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| PIRSF | |||||||||
| SMART |
SM00295
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9Y2L6 | ||||||||
| PhosphoSite | PhosphoSite-Q9Y2L6 | ||||||||
| TrEMBL | E9PGA7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 23150 | ||||||||
| UniGene | Hs.709671 | ||||||||
| RefSeq | NP_055938 | ||||||||
| HUGO | HGNC:24886 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS46863 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB023230 AC099328 AC112212 AC112221 AC135851 AK024086 BC028291 DA339318 | ||||||||
| GenPept | AAH28291 BAA76857 BAG51264 | ||||||||