InnateDB Protein
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IDBP-232914.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC26A1
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Protein Name
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solute carrier family 26 (sulfate transporter), member 1
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Synonyms
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EDM4; SAT-1; SAT1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000381532
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InnateDB Gene
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IDBG-6286 (SLC26A1)
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Protein Structure
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Function |
High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Mediates sulfate and oxalate transport. {ECO:0000269PubMed:12713736}.
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Subcellular Localization |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis, brain, small intestine, colon, and lung. {ECO:0000269PubMed:12713736}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008271
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secondary active sulfate transmembrane transporter activity
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GO:0015108
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chloride transmembrane transporter activity
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GO:0015116
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sulfate transmembrane transporter activity
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GO:0015301
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anion:anion antiporter activity
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GO:0019531
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oxalate transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H2B4
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PhosphoSite |
PhosphoSite-Q9H2B4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10861
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UniGene |
Hs.669836
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RefSeq |
NP_602297
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HUGO |
HGNC:10993
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OMIM |
610130
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CCDS |
CCDS33933
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HPRD |
15361
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IMGT |
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EMBL |
AC019103
AF297659
AK292747
AY124771
BC015517
CH471131
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GenPept |
AAG22075
AAH15517
AAM94171
BAF85436
EAW82628
EAW82629
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