Homo sapiens Protein: TMPRSS12
Summary
InnateDB Protein IDBP-233033.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMPRSS12
Protein Name transmembrane (C-terminal) protease, serine 12
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000381476
InnateDB Gene IDBG-32875 (TMPRSS12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity In testis, expressed in spermatocytes and spermatids. Expressed in colorectal cancer (at protein level). {ECO:0000269PubMed:23436708}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86WS5
PhosphoSite PhosphoSite-Q86WS5
TrEMBL
UniProt Splice Variant
Entrez Gene 283471
UniGene Hs.125571
RefSeq NP_872365
HUGO HGNC:28779
OMIM
CCDS CCDS44881
HPRD 07133
IMGT
EMBL AC008121 AC013244 BC048112
GenPept AAH48112