InnateDB Protein
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IDBP-233752.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TXLNG
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Protein Name
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taxilin gamma
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000381222
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InnateDB Gene
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IDBG-47575 (TXLNG)
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Protein Structure
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Function |
May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression. {ECO:0000269PubMed:15911876, ECO:0000269PubMed:18068885}.
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Subcellular Localization |
Nucleus membrane {ECO:0000269PubMed:15911876}. Cytoplasm, cytosol {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas. {ECO:0000269PubMed:15184072}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
18
[view]
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Protein-Protein |
18
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR026183
Taxilin family
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PFAM |
PF09728
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NUQ3
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PhosphoSite |
PhosphoSite-Q9NUQ3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
55787
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UniGene |
Hs.718291
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RefSeq |
NP_001162154
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HUGO |
HGNC:18578
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OMIM |
300677
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CCDS |
CCDS55373
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HPRD |
06478
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IMGT |
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EMBL |
AF143740
AK002071
AL929302
AY739713
BC101572
BC101576
BX004861
CH471074
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GenPept |
AAF70546
AAI01573
AAI01577
AAW65982
BAA92068
CAI41279
CAI41713
EAW98918
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