InnateDB Protein
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IDBP-233811.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TMEM123
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Protein Name
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transmembrane protein 123
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000381204
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InnateDB Gene
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IDBG-69084 (TMEM123)
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Protein Structure
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Function |
Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. {ECO:0000269PubMed:11481458}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Not expressed in ovary. Expressed in keratinocytes. {ECO:0000269PubMed:11481458, ECO:0000269PubMed:12752121}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N131
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PhosphoSite |
PhosphoSite-Q8N131
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TrEMBL |
E9PKT4
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UniProt Splice Variant |
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Entrez Gene |
114908
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UniGene |
Hs.742016
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RefSeq |
NP_443164
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HUGO |
HGNC:30138
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OMIM |
606356
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CCDS |
CCDS41702
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HPRD |
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IMGT |
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EMBL |
AK075420
AP000942
AP001830
AY008283
AY157580
AY358696
BC032296
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GenPept |
AAG21694
AAH32296
AAO13164
AAQ89059
BAC11610
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