InnateDB Protein
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IDBP-23391.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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UPK3B
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Protein Name
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uroplakin 3B
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000257632
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InnateDB Gene
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IDBG-409323 (UPK3B)
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Protein Structure
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Function |
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000269PubMed:12446744}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
GO:0007186
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G-protein coupled receptor signaling pathway
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GO:0010629
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negative regulation of gene expression
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BT76
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
80761
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UniGene |
Hs.488861
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RefSeq |
NP_085047
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HUGO |
HGNC:21444
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OMIM |
611887
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CCDS |
CCDS5588
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HPRD |
15626
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IMGT |
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EMBL |
AC004980
AC006972
AC007003
AC007078
AC114737
AK056760
AK290096
AY233462
BC004304
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GenPept |
AAH04304
AAO89507
AAS07526
BAF82785
BAG51807
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