Version 5.4
Homo sapiens Protein: SERPINB8
Summary
InnateDB Protein IDBP-234135.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB8
Protein Name serpin peptidase inhibitor, clade B (ovalbumin), member 8
Synonyms CAP2; PI8;
Species Homo sapiens
Ensembl Protein ENSP00000381072
InnateDB Gene IDBG-4599 (SERPINB8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 8 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P50452
PhosphoSite PhosphoSite-P50452
TrEMBL C9JVA8
UniProt Splice Variant
Entrez Gene 5271
UniGene Hs.618476
RefSeq
HUGO HGNC:8952
OMIM 601697
CCDS CCDS11991
HPRD 03412
IMGT
EMBL AC009802 AK300391 BC034528 BX571754 CH471096 L40377
GenPept AAC41939 AAH34528 BAG62124 CAE11879 EAW63163 EAW63165

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca