Version 5.4
Homo sapiens Protein: GADL1
Summary
InnateDB Protein IDBP-23461.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GADL1
Protein Name glutamate decarboxylase-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000282538
InnateDB Gene IDBG-23459 (GADL1)
Protein Structure
UniProt Annotation
Function May catalyze the decarboxylation of aspartate, cysteine sulfinic acid, and cysteic acid to beta-alanine, hypotaurine and taurine, respectively. Does not exhibit any decarboxylation activity toward glutamate. {ECO:0000269PubMed:23038267}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004068 aspartate 1-decarboxylase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0019752 carboxylic acid metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002129 Pyridoxal phosphate-dependent decarboxylase
IPR015424 Pyridoxal phosphate-dependent transferase
PFAM PF00282
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZQY3
PhosphoSite PhosphoSite-Q6ZQY3
TrEMBL
UniProt Splice Variant
Entrez Gene 339896
UniGene Hs.657052
RefSeq NP_997242
HUGO HGNC:27949
OMIM 615601
CCDS CCDS2649
HPRD 13557
IMGT
EMBL AC095029 AC138391 AK128643 AL832766 BC093701 BC111986
GenPept AAH93701 AAI11987 BAC87546

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca