InnateDB Protein
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IDBP-234714.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SEPT10
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Protein Name
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septin 10
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000380826
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InnateDB Gene
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IDBG-65245 (SEPT10)
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Protein Structure
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Function |
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). {ECO:0000305}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:12711328}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Using a GFP-fusion protein, detected in the nucleus. {ECO:0000269PubMed:12711328}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines. {ECO:0000269PubMed:12711328, ECO:0000269PubMed:15915442}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000038
Cell division protein GTP binding
IPR016491
Septin
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF00735
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PRINTS |
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PIRSF |
PIRSF006698
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9P0V9
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PhosphoSite |
PhosphoSite-Q9P0V9
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TrEMBL |
Q9H9P7
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UniProt Splice Variant |
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Entrez Gene |
151011
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UniGene |
Hs.596880
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RefSeq |
NP_848699
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HUGO |
HGNC:14349
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OMIM |
611737
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CCDS |
CCDS42726
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HPRD |
15325
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IMGT |
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EMBL |
AC011753
AC140485
AF146760
AK021681
AK022682
AK092033
BC020502
BC050345
CH471182
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GenPept |
AAF67469
AAH20502
AAH50345
AAY24142
BAB13873
BAB14176
BAG52471
EAW53864
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