InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NEB

Summary

InnateDB Protein

IDBP-235462.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEB

Protein Name

nebulin

Synonyms

NEB177D; NEM2;

Species

Homo sapiens

Ensembl Protein

ENSP00000380505

InnateDB Gene

IDBG-72258 (NEB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.

Experimentally validated
Total	31 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0008307	structural constituent of muscle

Biological Process

GO:0007517	muscle organ development
GO:0007525	somatic muscle development
GO:0030049	muscle filament sliding
GO:0030832	regulation of actin filament length
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005829	cytosol
GO:0015629	actin cytoskeleton
GO:0030018	Z disc
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000900 Nebulin repeat
IPR001452 SH3 domain
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR008966 Adhesion domain
IPR011511 Variant SH3 domain
IPR013998 Nebulin

PFAM

PF00880
PF00018
PF14604
PF07653

PRINTS

PR00452
PR00510

PIRSF

SMART

SM00227
SM00326

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt