InnateDB Protein
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IDBP-235710.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ERMN
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Protein Name
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ermin, ERM-like protein
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000380453
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InnateDB Gene
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IDBG-72862 (ERMN)
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Protein Structure
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Function |
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in adult and fetal brain. Expressed at intermediate levels in the lung and liver. {ECO:0000269PubMed:10574461}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008954
Moesin tail domain
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TAM6
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PhosphoSite |
PhosphoSite-Q8TAM6
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TrEMBL |
C9JN04
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UniProt Splice Variant |
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Entrez Gene |
57471
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UniGene |
Hs.443894
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RefSeq |
NP_001009959
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HUGO |
HGNC:29208
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OMIM |
610072
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CCDS |
CCDS42764
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HPRD |
13838
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IMGT |
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EMBL |
AB033015
AC016732
AK296477
AK296489
BC026345
CH471058
DQ334271
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GenPept |
AAH26345
AAY14889
ABC67251
BAA86503
BAG59118
BAG59126
EAX11448
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