InnateDB Protein
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IDBP-236045.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BLCAP
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Protein Name
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bladder cancer associated protein
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Synonyms
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BC10;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000380323
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InnateDB Gene
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IDBG-74305 (BLCAP)
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Protein Structure
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Function |
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B. {ECO:0000269PubMed:17031575}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Expressed in cervical tissues. Down-regulated in bladder invasive carcinoma, renal cell carcinoma and in primary cervical carcinoma. {ECO:0000269PubMed:10197429, ECO:0000269PubMed:16675915, ECO:0000269PubMed:19908260}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR018015
Bladder cancer-related BC10-like
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PFAM |
PF06726
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P62952
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PhosphoSite |
PhosphoSite-
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TrEMBL |
A2A2K9
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UniProt Splice Variant |
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Entrez Gene |
10904
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UniGene |
Hs.743223
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RefSeq |
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HUGO |
HGNC:1055
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OMIM |
613110
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CCDS |
CCDS13295
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HPRD |
16552
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IMGT |
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EMBL |
AF053470
AL109614
BC047692
BC071704
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GenPept |
AAC06370
AAH47692
AAH71704
CAC00475
CAM19261
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