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InnateDB Protein
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IDBP-236097.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RAPGEF4
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Protein Name
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Rap guanine nucleotide exchange factor (GEF) 4
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Synonyms
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2; CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000380274
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InnateDB Gene
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IDBG-75192 (RAPGEF4)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
10
[view]
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| Protein-Protein |
10
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
4 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0005085
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guanyl-nucleotide exchange factor activity
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| Biological Process |
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GO:0007264
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small GTPase mediated signal transduction
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GO:0043547
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positive regulation of GTPase activity
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR001895
Ras guanine-nucleotide exchange factors catalytic domain
IPR023578
Ras guanine nucleotide exchange factor domain
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| PFAM |
PF00617
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| PRINTS |
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| PIRSF |
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| SMART |
SM00147
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
H7BYQ0
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| UniProt Splice Variant |
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| Entrez Gene |
11069
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| UniGene |
Hs.604801
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| RefSeq |
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| HUGO |
HGNC:16626
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| OMIM |
606058
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| CCDS |
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| HPRD |
06929
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| IMGT |
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| EMBL |
AC009484
AC018712
AC019046
AC104086
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| GenPept |
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Version 5.4