Version 5.4
Homo sapiens Protein: CYTH3
Summary
InnateDB Protein IDBP-236866.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYTH3
Protein Name cytohesin 3
Synonyms ARNO3; GRP1; PSCD3;
Species Homo sapiens
Ensembl Protein ENSP00000379967
InnateDB Gene IDBG-8069 (CYTH3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
Biological Process
GO:0030155 regulation of cell adhesion
GO:0032012 regulation of ARF protein signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0048193 Golgi vesicle transport
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000904 Sec7 domain
IPR001849 Pleckstrin homology domain
PFAM PF01369
PF00169
PRINTS
PIRSF
SMART SM00222
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 9265
UniGene Hs.702333
RefSeq
HUGO HGNC:9504
OMIM 605081
CCDS
HPRD 05469
IMGT
EMBL AJ005197 AJ223957 BC028717 CH236963 CH878731
GenPept AAH28717 CAA06434 CAA11686 EAL23717 EAW55046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca