Version 5.4
Homo sapiens Protein: TMEM102
Summary
InnateDB Protein IDBP-237221.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM102
Protein Name transmembrane protein 102
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379815
InnateDB Gene IDBG-24980 (TMEM102)
Protein Structure
UniProt Annotation
Function Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway. {ECO:0000269PubMed:17828305}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:17828305}; Single-pass membrane protein {ECO:0000269PubMed:17828305}. Note=Although it is found at the cell surface, the majority of the molecules seems to be located in intracellular compartments.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0034097 response to cytokine
GO:0045785 positive regulation of cell adhesion
GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:2000406 positive regulation of T cell migration
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N9M5
PhosphoSite PhosphoSite-Q8N9M5
TrEMBL
UniProt Splice Variant
Entrez Gene 284114
UniGene Hs.655662
RefSeq XP_005256671
HUGO HGNC:26722
OMIM 613936
CCDS CCDS11104
HPRD 08215
IMGT
EMBL AK094197 BC046189 CH471108
GenPept AAH46189 BAC04306 EAW90189 EAW90190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca