InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MPP6

Summary

InnateDB Protein

IDBP-237418.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MPP6

Protein Name

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000379737

InnateDB Gene

IDBG-9862 (MPP6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Abundant in testis, brain, and kidney with lower levels detectable in other tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	25 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006461

protein complex assembly

Cellular Component

GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR004172 L27
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR014775 L27, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM