InnateDB Protein
|
IDBP-237509.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
KLRC3
|
Protein Name
|
killer cell lectin-like receptor subfamily C, member 3
|
Synonyms
|
NKG2-E; NKG2E;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000379716
|
InnateDB Gene
|
IDBG-18940 (KLRC3)
|
Protein Structure
|
|
Function |
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
|
Subcellular Localization |
Membrane; Single-pass type II membrane protein.
|
Disease Associations |
|
Tissue Specificity |
Natural killer cells.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0004888
|
transmembrane signaling receptor activity
|
GO:0030246
|
carbohydrate binding
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001304
C-type lectin
IPR008646
Herpesvirus UL45-like
IPR016187
C-type lectin fold
|
PFAM |
PF00059
PF05473
|
PRINTS |
|
PIRSF |
|
SMART |
SM00034
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q07444
|
PhosphoSite |
PhosphoSite-Q07444
|
TrEMBL |
Q71V82
|
UniProt Splice Variant |
|
Entrez Gene |
3823
|
UniGene |
Hs.654362
|
RefSeq |
NP_002252
|
HUGO |
HGNC:6376
|
OMIM |
602892
|
CCDS |
CCDS41755
|
HPRD |
04203
|
IMGT |
|
EMBL |
AC022075
AC068775
AF027164
AF078550
AF350016
AF350017
AF461157
AJ001685
L14542
|
GenPept |
AAA16833
AAC17490
AAD46108
AAK83803
AAK83804
AAL65232
CAA04923
|
|
|