Version 5.4
Homo sapiens Protein: ZNF468
Summary
InnateDB Protein IDBP-237579.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF468
Protein Name zinc finger protein 468
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379690
InnateDB Gene IDBG-67151 (ZNF468)
Protein Structure
UniProt Annotation
Function May be involved in transcriptional regulation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Isoform 1 and isoform 2 are highly expressed in placenta, pancreas, and small intestine. Lower expression in colon, ovary, testis, prostate, thymus, spleen, kidney, and liver. No expression detected in heart and brain. {ECO:0000269PubMed:16144304}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
PFAM PF01352
PRINTS
PIRSF
SMART SM00349
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5VIY5
PhosphoSite PhosphoSite-Q5VIY5
TrEMBL M0QZR5
UniProt Splice Variant
Entrez Gene 90333
UniGene Hs.621021
RefSeq
HUGO HGNC:33105
OMIM
CCDS
HPRD 18344
IMGT
EMBL AC008813 AY442330 AY442331 CH471135 CR749381 CR936599
GenPept AAS01603 AAS01604 CAH18233 CAI56747 EAW72100

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca