Version 5.4
Homo sapiens Protein: GPRC5D
Summary
InnateDB Protein IDBP-237764.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPRC5D
Protein Name G protein-coupled receptor, family C, group 5, member D
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379624
InnateDB Gene IDBG-20601 (GPRC5D)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000269PubMed:11311935}; Multi-pass membrane protein {ECO:0000269PubMed:11311935}.
Disease Associations
Tissue Specificity Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscle and ovary. {ECO:0000269PubMed:11311935}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR017978 GPCR, family 3, C-terminal
PFAM PF00003
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NZD1
PhosphoSite PhosphoSite-Q9NZD1
TrEMBL F5GWX9
UniProt Splice Variant
Entrez Gene 55507
UniGene Hs.644599
RefSeq
HUGO HGNC:13310
OMIM 607437
CCDS
HPRD 07604
IMGT
EMBL AB083629 AB099817 AC007688 AF209923 BC069341 BC107077 BC107078
GenPept AAF72873 AAH69341 AAI07078 AAI07079 BAB89342 BAC79169

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca