Version 5.4
Homo sapiens Protein: WDR16
Summary
InnateDB Protein IDBP-237961.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR16
Protein Name WD repeat domain 16
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379521
InnateDB Gene IDBG-29746 (WDR16)
Protein Structure
UniProt Annotation
Function May play an essential role in the growth or survival of hepatocellular carcinoma (HCC). {ECO:0000269PubMed:15967112}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:15967112}.
Disease Associations
Tissue Specificity Highly expressed in testis. Up-regulated in hepatocellular carcinoma (HCC). {ECO:0000269PubMed:15967112}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N1V2
PhosphoSite PhosphoSite-Q8N1V2
TrEMBL
UniProt Splice Variant
Entrez Gene 146845
UniGene Hs.232270
RefSeq NP_001074025
HUGO HGNC:16053
OMIM 609804
CCDS CCDS42262
HPRD 14072
IMGT
EMBL AB065281 AC087501 AC118755 AK074435 AK094847 AK315679 BC025392
GenPept AAH25392 BAB83743 BAB85083 BAC04435 BAG38044

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca