Version 5.4
Homo sapiens Protein: UEVLD
Summary
InnateDB Protein IDBP-238011.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UEVLD
Protein Name UEV and lactate/malate dehyrogenase domains
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379500
InnateDB Gene IDBG-35088 (UEVLD)
Protein Structure
UniProt Annotation
Function Possible negative regulator of polyubiquitination. {ECO:0000269PubMed:12427560}.
Subcellular Localization
Disease Associations
Tissue Specificity Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes. {ECO:0000269PubMed:12427560}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006464 cellular protein modification process
GO:0008150 biological_process
GO:0015031 protein transport
GO:0044262 cellular carbohydrate metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001236 Lactate/malate dehydrogenase, N-terminal
IPR001557 L-lactate/malate dehydrogenase
IPR008883 Ubiquitin E2 variant, N-terminal
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
IPR022383 Lactate/malate dehydrogenase, C-terminal
PFAM PF00056
PF05743
PF02866
PRINTS PR00086
PIRSF PIRSF000102
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IX04
PhosphoSite PhosphoSite-Q8IX04
TrEMBL B4DWH4
UniProt Splice Variant
Entrez Gene 55293
UniGene Hs.407991
RefSeq NP_001248313
HUGO HGNC:30866
OMIM 610985
CCDS CCDS41624
HPRD 15608
IMGT
EMBL AC027544 AC112694 AF503350 AK001930 AK295501 AK296835 AK301537 AK314521 BC011011 BC064566 CD109744 CH471064 CR616778
GenPept AAH11011 AAH64566 AAN32950 BAA91985 BAG37116 BAG58421 BAG59405 BAG63036 EAW68380

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca