Version 5.4
Homo sapiens Protein: TEKT3
Summary
InnateDB Protein IDBP-238553.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TEKT3
Protein Name tektin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000379263
InnateDB Gene IDBG-31552 (TEKT3)
Protein Structure
UniProt Annotation
Function Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0030317 sperm motility
GO:0060271 cilium morphogenesis
GO:0080154 regulation of fertilization
Cellular Component
GO:0002080 acrosomal membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0036126 sperm flagellum
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000435 Tektin
PFAM
PRINTS PR00511
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXF9
PhosphoSite PhosphoSite-Q9BXF9
TrEMBL F5H5M8
UniProt Splice Variant
Entrez Gene 64518
UniGene Hs.414648
RefSeq NP_114104
HUGO HGNC:14293
OMIM 612683
CCDS CCDS11169
HPRD 18173
IMGT
EMBL AC005703 AF334676 AK057390 AK314327 BC031688 CH471108
GenPept AAH31688 AAK15340 BAB71464 BAG36974 EAW89942 EAW89943 EAW89944

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca