InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TEX11

Summary

InnateDB Protein

IDBP-238602.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TEX11

Protein Name

testis expressed 11

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000379226

InnateDB Gene

IDBG-74610 (TEX11)

Protein Structure

UniProt Annotation

Function

Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers (By similarity). {ECO:0000250}.

Subcellular Localization

Chromosome {ECO:0000250}. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes. {ECO:0000250}.

Disease Associations

Tissue Specificity

Testis-specific. Not expressed in adult ovaries. {ECO:0000269PubMed:18369460}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	29 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000712	resolution of meiotic recombination intermediates
GO:0006311	meiotic gene conversion
GO:0007060	male meiosis chromosome segregation
GO:0007130	synaptonemal complex assembly
GO:0007131	reciprocal meiotic recombination
GO:0007140	male meiosis
GO:0008584	male gonad development
GO:0009566	fertilization
GO:0043066	negative regulation of apoptotic process
GO:0051026	chiasma assembly