InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EHMT2

Summary

InnateDB Protein

IDBP-238926.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EHMT2

Protein Name

euchromatic histone-lysine N-methyltransferase 2

Synonyms

BAT8; C6orf30; G9A; GAT8; KMT1C; NG36;

Species

Homo sapiens

Ensembl Protein

ENSP00000379078

InnateDB Gene

IDBG-79489 (EHMT2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 117 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	117 [view]
Protein-Protein	113 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0018024	histone-lysine N-methyltransferase activity

Biological Process

GO:0034968	histone lysine methylation
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634	nucleus
GO:0005694	chromosome

Protein Structure and Domains

PDB ID

InterPro

IPR001214 SET domain
IPR002110 Ankyrin repeat
IPR003606 Pre-SET zinc-binding sub-group
IPR007728 Pre-SET domain
IPR020683 Ankyrin repeat-containing domain

PFAM

PF00856
PF00023
PF13606
PF05033
PF11929
PF12796

PRINTS

PR01415

PIRSF

SMART

SM00317
SM00248
SM00468

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt