Version 5.4
Homo sapiens Protein: LBH
Summary
InnateDB Protein IDBP-239808.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LBH
Protein Name limb bud and heart development homolog (mouse)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000378733
InnateDB Gene IDBG-239806 (LBH)
Protein Structure
UniProt Annotation
Function Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway. {ECO:0000269PubMed:17390236}.
Subcellular Localization Nucleus {ECO:0000269PubMed:17390236}. Cytoplasm {ECO:0000269PubMed:17390236}.
Disease Associations
Tissue Specificity Highly expressed in heart, and expressed at low levels in placenta, lung, skeletal muscle, kidney and liver. {ECO:0000269PubMed:17390236}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0010468 regulation of gene expression
GO:0030193 regulation of blood coagulation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR013294 Limb-bud-and-heart
PFAM
PRINTS PR01881
PIRSF PIRSF008130
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q53QV2
PhosphoSite PhosphoSite-Q53QV2
TrEMBL F8WC18
UniProt Splice Variant
Entrez Gene 81606
UniGene Hs.700372
RefSeq NP_112177
HUGO HGNC:29532
OMIM 611763
CCDS CCDS33173
HPRD 13965
IMGT
EMBL AC104698 AC109642 AK223541 AK314598 AL136703 BC109376 BC126434 BC130415 EF025586
GenPept AAI09377 AAI26435 AAI30416 AAY24349 ABK30936 BAD97261 BAG37169 CAB66638

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca