Version 5.4
| Homo sapiens Protein: CALN1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-239880.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CALN1 | ||||||||
| Protein Name | calneuron 1 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000378691 | ||||||||
| InnateDB Gene | IDBG-19152 (CALN1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning. {ECO:0000250}. | ||||||||
| Subcellular Localization | Golgi apparatus, trans-Golgi network membrane {ECO:0000305PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305PubMed:19338761}. Cytoplasm, perinuclear region {ECO:0000269PubMed:19338761}. Cell membrane {ECO:0000305PubMed:19338761}; Single-pass type IV membrane protein {ECO:0000305PubMed:19338761}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Brain specific. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR002048
EF-hand domain |
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| PFAM |
PF00036
PF13202 PF13405 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00054
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9BXU9 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | Q86UM7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 83698 | ||||||||
| UniGene | Hs.592750 | ||||||||
| RefSeq | XP_006716209 | ||||||||
| HUGO | HGNC:13248 | ||||||||
| OMIM | 607176 | ||||||||
| CCDS | CCDS5541 | ||||||||
| HPRD | 06209 | ||||||||
| IMGT | |||||||||
| EMBL | AC004845 AC004905 AC005011 AC006334 AC067941 AC092424 AC092785 AF282250 AK123862 AK313054 AY007302 BC020200 CH236952 CH471140 | ||||||||
| GenPept | AAG09620 AAH20200 AAK15155 AAP21872 AAP21889 AAS02041 AAS07466 AAS07507 BAG35885 BAG53974 EAL23970 EAX07902 | ||||||||