InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZBTB25

Summary

InnateDB Protein

IDBP-241022.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZBTB25

Protein Name

zinc finger and BTB domain containing 25

Synonyms

C14orf51; KUP; ZNF46;

Species

Homo sapiens

Ensembl Protein

ENSP00000378204

InnateDB Gene

IDBG-9157 (ZBTB25)

Protein Structure

UniProt Annotation

Function

May be involved in transcriptional regulation.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Expressed mainly in hematopoietic cells and testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0010467	gene expression

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like

PFAM

PF00096
PF00651

PRINTS

PIRSF

SMART

SM00225
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P24278

PhosphoSite

PhosphoSite-P24278

TrEMBL

UniProt Splice Variant

Entrez Gene

7597

UniGene

Hs.734145

RefSeq

XP_005268106

HUGO

HGNC:13112

OMIM

194541

CCDS

CCDS9765

HPRD

01926

IMGT

EMBL

AK098181 BC035804 CH471061 X16576

GenPept

AAH35804 BAG53588 CAA34595 EAW80861