InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MT1X

Summary

InnateDB Protein

IDBP-241499.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MT1X

Protein Name

metallothionein 1X

Synonyms

MT-1l; MT1;

Species

Homo sapiens

Ensembl Protein

ENSP00000377995

InnateDB Gene

IDBG-32422 (MT1X)

Protein Structure

UniProt Annotation

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	5 [view]
Protein-DNA	2 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0006882	cellular zinc ion homeostasis
GO:0007263	nitric oxide mediated signal transduction
GO:0010038	response to metal ion
GO:0010273	detoxification of copper ion
GO:0036018	cellular response to erythropoietin
GO:0045926	negative regulation of growth
GO:0071276	cellular response to cadmium ion
GO:0071294	cellular response to zinc ion