InnateDB Protein
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IDBP-24159.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PPP1R42
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Protein Name
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protein phosphatase 1, regulatory subunit 42
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000315035
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InnateDB Gene
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IDBG-24155 (PPP1R42)
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Protein Structure
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Function |
Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Colocalizes with alpha tubulin to the manchette of developing spermatids. Detected to nuclear rim in pachytene spermatocytes. Detected at nuclear surface, opposite the acrosome in elongating spermatids. Detected at the microtubule- organizing center (MTOC). Localized to the centrosomal region of late-stage spermatids (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001611
Leucine-rich repeat
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PFAM |
PF00560
PF13504
PF13855
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7Z4L9
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PhosphoSite |
PhosphoSite-Q7Z4L9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
286187
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UniGene |
Hs.736151
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RefSeq |
NP_001013648
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HUGO |
HGNC:33732
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OMIM |
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CCDS |
CCDS34902
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HPRD |
14573
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IMGT |
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EMBL |
AC110998
BC055413
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GenPept |
AAH55413
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