Version 5.4
Homo sapiens Protein: MRRF
Summary
InnateDB Protein IDBP-241841.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRRF
Protein Name mitochondrial ribosome recycling factor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377850
InnateDB Gene IDBG-83804 (MRRF)
Protein Structure
UniProt Annotation
Function Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006412 translation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR023584 Ribosome recycling factor domain
PFAM PF01765
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96E11
PhosphoSite PhosphoSite-Q96E11
TrEMBL X6RDS5
UniProt Splice Variant
Entrez Gene 92399
UniGene Hs.735577
RefSeq NP_954646
HUGO HGNC:7234
OMIM 604602
CCDS CCDS48013
HPRD 06856
IMGT
EMBL AK291603 AK291809 AK292790 AK298046 AK300718 AK316266 AL162424 BC013049 BC053604 CH471090
GenPept AAH13049 AAH53604 BAF84292 BAF84498 BAF85479 BAH12711 BAH13333 BAH14637 CAI14707 CAI14708 CAI14711 CAI14712 CAI14713 EAW87525

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca