Version 5.4
Homo sapiens Protein: SENP7
Summary
InnateDB Protein IDBP-242275.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SENP7
Protein Name SUMO1/sentrin specific peptidase 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377647
InnateDB Gene IDBG-47736 (SENP7)
Protein Structure
UniProt Annotation
Function Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full- length SUMO proteins to their mature forms. {ECO:0000269PubMed:18799455}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003653 Peptidase C48, SUMO/Sentrin/Ubl1
PFAM PF02902
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BQF6
PhosphoSite PhosphoSite-Q9BQF6
TrEMBL
UniProt Splice Variant
Entrez Gene 57337
UniGene Hs.605544
RefSeq
HUGO HGNC:30402
OMIM 612846
CCDS
HPRD 07154
IMGT
EMBL AB051494 AC068764 AC073861 AC110994 AF199458 AF217504 AL136599 BC129988 BX537943
GenPept AAG09703 AAI29989 AAL25651 BAB21798 CAB66534 CAD97911

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca